Therapeutic Effects of Theta-Burst Stimulation on severity of depression and cognitive functions in major depressio
Phase 3
Recruiting
- Conditions
- A treatment option for refracfory depression
- Registration Number
- JPRN-UMIN000011856
- Lead Sponsor
- Taipei Veterans General Hospital, Taiwan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Not provided
Exclusion Criteria
No major systemic illness(e.g.,severe arrhythmia);no neurological disorders(e.g., neuro-stimulators, stroke, seizure, traumatic brain injury); Not in pregnant; No brain implants; No pacemakers; No brain surgery past history
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maudsley staging scoring questionnaires (baseline); Depressive symptoms: Hamilton Depression Rating Scale-17 (HDRS-17), Depression Subscales for Somatic Symptoms (DSSS), Short-form McHill Pain Questionnaire(MPQ) and Visual Analogue Scores (VAS) Manic symptoms: Young Mania Rating Scales (YMRS) Quality of life: MOS SF-12 quality of life rating scales
- Secondary Outcome Measures
Name Time Method erocognitive testings will be also performed twice, baseline and 2 weeks post-treatment, to check their attention (Test for Attentional Performance) and executive function (Wisconsin Card Sorting Tests). 3T MRI and 18F-FDG PET