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临床试验/CTRI/2022/12/048149
CTRI/2022/12/048149尚未招募不适用

Construction and Validation of Anaglyph dichoptic vision chart and its application in detecting suppression in paediatric eye screening.

Sankara eye hospital Bangalore1 个研究点 分布在 1 个国家目标入组 4,099 人开始时间: 2022年12月20日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
4,099
试验地点
1
主要终点
Mono ocular visual acuity interpreted from binocular chart with that recorded using standard ETDRS chart

研究概览

简要总结

Amblyopia being the most common cause of monocular vision loss in children, is defined as decreased best-corrected visual acuity (VA) in one, or less frequently both eyes, in the absence of any obvious structural anomalies or ocular disease.

The gold standard for amblyopia screening is visual acuity testing and most vision screening programs still rely on visual acuity charts as their primary screening test for amblyopia. Visual acuity testing requires cooperation from the children and needs to be done in each eye separately. It is subject to errors depending on if children have memorized the charts, peeps from other eye while testing, and so on.

Suppression of an eye is a subconscious adaptation by a person’s brain to eliminate double vision by ignoring all or part of the image of one of the eyes, and is an important component of amblyopia. The currently options available commercially for assessing suppression are the Four base out prism test, Worth Four dot test, Polarized four dot test.

Most commercial methods of testing suppression measure only foveal or central suppression at one test distance.Also,current clinical tests for suppression tend to verify the presence or absence of suppression rather than giving a quantitative measurement of the degree of suppression.

In this study, we aim to develop a new chart based on dichoptic principles thus detecting suppression and quantifying it by measuring the size of suppression scotoma,testing mono-ocular visual acuity binocularly and validating it with standard ETDRS chart which is used for screening amblyopia in school going children currently.

研究设计

研究类型
Observational

入排标准

年龄范围
8.00 Year(s) 至 15.00 Year(s)(—)
性别
All

入选标准

  • •Verbal Children between 8-15 years of age.

排除标准

  • •Non verbal children Children with developmental delay or low IQ interfering with visual acuity testing.

结局指标

主要结局

Mono ocular visual acuity interpreted from binocular chart with that recorded using standard ETDRS chart

时间窗: Immediate

次要结局

  • Size of suppression scotoma(Immediate)

研究者

发起方
Sankara eye hospital Bangalore
申办方类型
Research institution and hospital

研究点 (1)

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