A multicenter clinical study for Yiqi Tongluo Granule in the treatment of angina pectoris caused by non obstructive coronary microvascular disease

Not Applicable

• Conditions: Angina pectoris

• Registration Number: ITMCTR1900002698
• Lead Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1) Have symptoms of myocardial ischemia, such as exertive or resting angina;
(2) ECG changes or exercise load test were positive during the attack;
(3) No stenosis more than 50% was found by coronary angiography;
(4) D-spect evaluation CFR < 2; aged 40-80 years, gender unlimited;
(5) The syndrome differentiation of TCM is Qi deficiency and blood stasis.
(6) Patients and their families are willing to cooperate and meet the exclusion criteria.

Exclusion Criteria

(1) Grade 4 cardiac function or pulmonary edema;
(2) Severe primary brain and lung diseases and liver and kidney dysfunction;
(3) Allergic to traditional Chinese medicine;
(4) Patients with malignant diseases;
(5) Severe inflammatory disease;
(6) patients with bleeding diseases;
(7) malignant arrhythmia;
(8) acute coronary syndrome;
(9) Mental patients;
(10) Pregnant or nursing women;
(11) Those who participated in other clinical trials within the past month.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Coronal Blood Flow Reserve (CFR);

Secondary Outcome Measures

Name	Time	Method
Clinical symptoms;Major cardiovascular events;Contraction end volume;Diastolic end volume;The quality of life;