To Evaluate TheEffect of Laksha Choorna in Asridgara (Dysfunctional UterineBleeding)

Phase 2/3

Not yet recruiting

• Conditions: Other specified abnormal uterine and vaginal bleeding. Ayurveda Condition: ASRUGDARAH/RAKTAPRADARAH,

• Registration Number: CTRI/2023/06/053629
• Lead Sponsor: Dr B Manisha Reddy

Brief Summary

*Asrigdara* is a common menstrual disorder affecting women. It is characterized by excessive prolonged menstrual or intermenstrual bleeding which interferes with women’s physical, emotional and social quality of life. In modern science it can be correlated with Abnormal Uterine Bleeding. Dysfunctional uterine bleeding is one among Abnormal uterine bleeding without any clinically detectable Organic Cause. The Rate of prevalence of AUB in India is around 17.9%. In contemporary science management protocol includes interventions like Hormonal therapy, Anti prostaglandins and antifibrinolytic agentsand further advices to surgical interventions like uterine curettage, endometrial ablation and Hysterectomy, which has their own limitations, high costs with associated side effects. Ayurvedic classics have described varieties of treatment options in the management of *Asrigdara*, which are non-hormonal, non-surgical, effective drugs without any adverse effects. Among them *Laksha choorna* and *Pushyanuga choorna* are *shamana aushadhi’s* having properties like *kashaya rasa pradhana, pitta* *shamaka* and *rakta stambaka* in action found to be effective in *Asrigdara*. *Laksha choorna* which is a cost effective, commonly available drug and can be prepared easily. Hence the study has been taken as **“A** **Randomized controlled clinical study to evaluate the effect of *Laksha choorna* in *Asrigdara* (dysfunctional uterine bleeding)’’.**

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-06-06
• Study Start: 2023-06-16

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• 1 Subjects presenting with pratyatma lakshanas of Asrigdara (Raja atipravruthi,DeerghaKalanubhandhi, Anruthavalpamapi) with Raja atipravruthi as a main symptom.
• Ages for the study: 20-45years.
• Subjects ready to sign the informed consent form.

Exclusion Criteria

• 1.Participants who are not willing for trial.
• 2.Structural abnormalities involvement in uterus.
• 3.Uterine polyp.
• 4.Carcinoma of cervix.
• 5.Fibroid uterus.
• 6.Adenomyosis of the uterus.
• 7.Coagulation disorders like Haemophilia, Leukaemia, sickle cell anaemia.
• 8.Systemic diseases like Diabetes mellitus, Hypertension, epileptic disorders.
• 9.Haemoglobin less than 6 g/dL 10.Women using Intra Uterine contraceptive Devices or oral contraceptive pills.
• 11.Bleeding after menopause.
• 12.Miscarriages.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in Amount & duration of bleeding	fifth day of menstrual cycle for two consecutive menstrual cycles | Observational | Followup fifth day of third Menstrual cycle

Secondary Outcome Measures

Name	Time	Method
to analyse condtion of asrigdara & treat by ayurveda principles	fifth day of menstrual cycle for two consecutive menstrual cycles

Trial Locations

Locations (1)

SDM Ayurveda Hospital Bengaluru; 🇮🇳 Bangalore, KARNATAKA, India

SDM Ayurveda Hospital Bengaluru

🇮🇳Bangalore, KARNATAKA, India

Dr B Manisha Reddy

Principal investigator

9703353969

bmanishareddy@sdmayurbangalore.in