Sensory testing of the skin using heat stimulation In healthy volunteers and neuropathic Pain Patients

• Conditions: chronische pijn; neuropathic pain; pain

• Registration Number: NL-OMON37526
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 84

Inclusion Criteria

Patient inclusion criteria. (i) Patients diagnosed with CRPS-1, small-fiber neuropathy, central neuropathic pain or fibromyalgia, according to the guidelines of the IASP or other professional pain societies (eg., Netherlands Society of Anesthesiologists); (ii) a pain score of 5 or higher; (iii) age between 18 and 75 years; (iv) being able to give written informed consent.;Volunteer inclusion criteria. Healthy volunteers in the age range 18-75 years of either sex.

Exclusion Criteria

Patient and volunteer exclusion criteria. (i) Unable to give written informed consent; (ii) medical disease such as renal, liver, cardiac, vascular (incl. hypertension) infectious disease; (iii) increased intracranial pressure; (iv) epilepsy; (v) psychosis; (vi) glaucoma; (vii) a history of cerebro-vascular accident < 1 year; (viii) pregnancy; and (ix) obesity (BMI > 30).

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Pain scores in response to a heat stimulus</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>None</p><br>