Quantitative sensory testing and intraepidermal nerve fibre density for improved diagnosis of Fabry disease.

Completed

• Conditions: Anderson-Fabry disease; Fabry disease; 10027424

• Registration Number: NL-OMON37662
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Adult males and females with signs or symptoms possibly attributable to Fabry disease.

Exclusion Criteria

Patient is unwilling to participate

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To determine if alterations of intraepidermal nerve fiber density and<br /><br>quantitative sensory testing are present in patients with a possible diagnosis<br /><br>of Fabry disease, but without clinical signs and symptoms of small fiber<br /><br>neuropathy.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To evaluate if alterations of intraepidermal nerve fiber density and<br /><br>quantitative sensory testing can contribute to the diagnosis of Fabry disease<br /><br>in patients with a possible diagnosis of Fabry disease, but without clinical<br /><br>signs and symptoms of small fiber neuropathy.</p><br>