*Characteristics of Quantitative Sensory Testing in ACNES patients compared to healthy controls; a pilot study.*

Completed

• Conditions: abdominal wall pain; entrapment neuropathy; 10034606

• Registration Number: NL-OMON43275
• Lead Sponsor: Maxima Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

ACNES group:
- Diagnosis of ACNES based upon 3 of 4 of the following characteristics:
- Sensory disturbances at triggerpoint site
- Positive Carnet*s sign at triggerpoint site
- Positive Pinch sign at triggerpoint site
- Positive modified rectus sheath block (>50% pain reduction)
- Unilateral
- Subject is at least 18 years old but younger than 55
- Subject is able and willing to comply with the follow-up schedule and protocol
- Subject is able to provide written informed consent;Healthy controls:
- Subject is at least 18 years old but younger than 55
- Subject is able and willing to comply with the follow-up schedule and protocol
- Subject is able to provide written informed consent

Exclusion Criteria

- Female subject of childbearing potential is pregnant
- Significant comorbidity
- Previous abdominal open surgery with significant scars
- Skin lesions at target sites
- (Other) pain syndromes such as fibromyalgia, carpal tunnel syndrome, etc.
- Neurological disorders associated with sensory loss, e.g. diabetic neuropathy, MS, etc.
- Attention deficit disorders
- Opioid use or pain treatment regimen that can*t be temporarily interrupted;Only for healthy controls:
(history of) ACNES

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Significant differences between ACNES patients, healthy volunteers and database<br /><br>reference values on different modalities of the standardized QST protocol of<br /><br>the German Research Network on Neuropathic Pain (DFNS). This includes Cold/Warm<br /><br>detection threshold, Cold/Heat pain threshold, Pin prick sensitivity, Wind-up,<br /><br>and pressure pain thresholds. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoint is differences in therapy outcomes in the ACNES group by<br /><br>sensory profile.</p><br>