The effects of a combined functional gait- and strength training on stability of walking and rate of bone turn over in healthy elderly.
Recruiting
- Conditions
- AgeingInactivity
- Registration Number
- NL-OMON23185
- Lead Sponsor
- VU University
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. 65-75 years;
2. Male or femaie;
Exclusion Criteria
Vacscular-, neurological- or musculosceletal diseases that would interfere with the ability to walk, the use of walking aids or contra-indications for strength testing.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Stability of unperturbed walking (Local dynamic stability and variability of walking);<br /><br>2. Stability of perturbed walking (size of deflection from normal walking pattern and speed of return to normal walking pattern);<br /><br>3. Indicators of bone turnover (markers of bonedegeneration: CTx; markers of bone synthesis: osteocalcine en P1NP).
- Secondary Outcome Measures
Name Time Method 1. (Changes in) quality of the heel bone (ultrasound);<br /><br>2. (Changes in) systemic growth factors (e.g. IGF-1 and Myostatin);<br /><br>3. (Changes in) efficiency of walking (O2/kg/m);<br /><br>4. Relation between (changes in) muscle performance parameters and (changes in) stability of walking;<br /><br>5. Relation between (changes in) bone turnover parameters and (changes in) muscle performance parameters.