Investigation of Rocaltrol prescribed before parathyroidectomy surgery to assess the effect of hypocalcemia after surgery in patients with parathyroid edenoma

Phase 3

• Conditions: Primary hyperparathyroidism; Investigation of Rocaltrol prescribed before parathyroidectomy surgery to assess the effect of hypocalcemia after surgery in patients with parathyroid edenoma.; E21.0

• Registration Number: IRCT20220822055773N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Primary hyperparathyroidism patients operated in the surgery department of Shariati Hospital

Exclusion Criteria

Patients who have hyperparathyroid crisis before the operation and those who are going to remove all 4 parathyroid glands (patients with MEN) are excluded from the study.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The use of oral rocartrol before surgery to reduce hypocalcemic symptoms and reduce the need for hospitalization in primary hyperparathyroidism patients. Timepoint: PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Method of measurement: Demographic information is obtained by interviewing the patient. From the results of the laboratory, data related to the measurement of calcium, PTH, Vit D, Alk.p, through ultrasound or scanning of the adenoma site and through clinical examination of hypocalcemic symptoms are extracted.

Secondary Outcome Measures

Name	Time	Method
PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Timepoint: PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Method of measurement: Demographic information is obtained by interviewing the patient. From the results of the laboratory, data related to the measurement of calcium, PTH, Vit D, Alk.p, through ultrasound or scanning of the adenoma site and through clinical examination of hypocalcemic symptoms are extracted.