Impact of initial coagulation and fibrinolytic markers on mortality in severe blunt trauma patients:A multicenter retrospective observational study.
Not Applicable
- Conditions
- Trauma
- Registration Number
- JPRN-UMIN000031264
- Lead Sponsor
- Rinku General Medical Center, Senshu Trauma and Critical Care Center
- Brief Summary
CART analysis revealed that the initial discriminator was fibrinogen (cut-off 130) and the second discriminator was D-dimer (cut-off 110 in the lower fibrinogen subgroup; 118 in the higher fibrinogen subgroup). The 28-day mortality was 90.0% (lower fibrinogen, higher D-dimer), 27.8% (lower fibrinogen, lower D-dimer), 27.7% (higher fibrinogen, higher D-dimer) and 3.4% (higher fibrinogen, lower D-dimer).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 666
Inclusion Criteria
Not provided
Exclusion Criteria
cardiopulmonary arrest on arrival, transferred from other hospitals, pregnant women, patients whose coagulation or fibrinolytic markers were not examined at emergency department
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method