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Clinical Trials/NCT03048292
NCT03048292
Completed
Not Applicable

Reducing Disparities in Mechanical Embolectomy Access for Patients of New York City Via a Mobile Interventional Stroke Team: Systems of Care and Time-To-Treatment

Icahn School of Medicine at Mount Sinai4 sites in 1 country191 target enrollmentJune 2016
ConditionsAcute Stroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Stroke
Sponsor
Icahn School of Medicine at Mount Sinai
Enrollment
191
Locations
4
Primary Endpoint
Treatment times
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Endovascular treatment has recently become the recommended therapy for acute stroke after the publication of five randomized trials (MR CLEAN1, ESCAPE2, EXTEND IA3, SWIFT PRIME4, REVASCAT5) in 2015 that demonstrate its efficacy. Hospitals need to adapt to these updated stroke care guidelines, and many hospitals are not appropriately equipped for neurointerventional procedures. Decreased time to treatment is associated with favorable clinical outcomes, and best practices to optimize workflow between comprehensive stroke centers and secondary hospitals have become an important area of study. This prospective study is being conducted on acute stroke cases within the Mount Sinai Health System from 1 June 2016 up until 31 December 2018. The researchers would like to evaluate how variable methods of interventional service delivery for acute stroke affect clinical measures and outcomes.

More specifically, the researchers are conducting this study in order to determine whether outcomes of neurointervention for large vessel occlusion in stroke, for patients presenting to and receiving treatment at a comprehensive stroke center, will be superior to that delivered by a mobilized intervention team at a central satellite hospital. In particular, the hypothesis is that factors affecting outcome include presentation to secondary hospital, delays with transfer including traffic conditions and time of day, and the acquisition of complex imaging within secondary hospitals.

Registry
clinicaltrials.gov
Start Date
June 2016
End Date
July 16, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Treatment times

Time Frame: 90 days

Time between first hospital arrival and final recanalization

Secondary Outcomes

  • Time to groin puncture procedure(3 months)
  • NIHSS(90 days)
  • Time of EMS contact to groin puncture(90 days)
  • modified Rankin Scale (mRS)(90 days)

Study Sites (4)

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