RAAS-blockade in type II diabetes: added effects of a low sodium diet and diuretics.
Completed
- Conditions
- diabetesType II diabetes1001265310029149
- Registration Number
- NL-OMON35646
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 55
Inclusion Criteria
Age between 18-70 years
Type II diabetes
Albuminuria > 30 mg/24h
Stable 24h creatinine clearance >30 ml/min/1,73 m2
Exclusion Criteria
Contraindication for the use of lisinopril or hydrochlorothiazide
Type I diabetes
Myocardial infarction or stroke within 3 month prior to the research
Kidneydisease unrelated to diabetes or hypertension
Proteinuria >3 gr/24h
Hypertension unresponsive to therapy during run-in period
Inabilty for informed consent
Incompliance to diet or studymedication
Inaccordance with inclusioncriteria
Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method