RAAS-blockade in type II diabetes: added effects of dietary sodum restriction and diuretics.
Completed
- Conditions
- Diabetes Mellitus, proteinuria, albuminuria, hypertension, kidney disease, dietary sodium, RAAS-blockade
- Registration Number
- NL-OMON24944
- Lead Sponsor
- niversity Medical Center Groningen (UMCG)
- Brief Summary
Effects of sodium restriction and hydrochlorothiazide on RAAS blockade efficacy in diabetic nephropathy: a randomised clinical trial.<br> Kwakernaak AJ, Krikken JA, Binnenmars SH, Visser FW, Hemmelder MH, Woittiez AJ, Groen H, Laverman GD, Navis G; Holland Nephrology Study (HONEST) Group.<br> Lancet Diabetes Endocrinol. 2014 May;2(5):385-95. doi: 10.1016/S2213-8587(14)70030-0. Epub 2014 Mar 5. <br><br> PMID nummer van de plublicatie is: 24795252
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 55
Inclusion Criteria
1. Diabetic nephropathy;
2. Diabetes mellitus type II;
Exclusion Criteria
1. Diabetes mellitus type I;
2. Myocardial infarction or other cardiovascular or cerebrovascular event within the last 3 months prior to entry into the study;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Albuminuria response;<br /><br>2. Blood pressure response.
- Secondary Outcome Measures
Name Time Method Extracellular fluid volume response.