The timing of administration of a steroid, dexamethasone, on the postoperative relief from pain in women undergoing uterus removal surgery.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/02/031024
- Lead Sponsor
- Dr Premangshu Ghoshal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients undergoing open total abdominal hysterectomy under spinal anaesthesia
Exclusion Criteria
Refusal to give consent,
Known history of Corticosteroid hypersensitivity,
Diabetes Mellitus patients,
Increased Preoperative TLC Count,
Patients already receiving corticosteroid or immunosuppresive drugs preoperatively,
Previous history of gastric ulcer,
Receiving other analgesics,
Patients for whom general anesthesia will be required because of unexpectedly prolonged surgery for any reason or because of any complication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VASTimepoint: 6 hours
- Secondary Outcome Measures
Name Time Method 24 hour incidence of PONVTimepoint: Upto 24 hours post-operatively;Cumulative 24 hours Opioid UseTimepoint: Upto 24 hours post-operatively;Difference in VASTimepoint: 24 hours;Duration of post-operative hospital stay in daysTimepoint: Until hospital discharge;Duration of stay in recovery unitTimepoint: Upto 6 hours post-operatively;Incidence of any wound infectionTimepoint: Until hospital discharge;Time in minutes to request for first analgesicTimepoint: Upto 8 hours post-operatively;Time to passage of faecesTimepoint: Until hospital discharge;Time to regression of motor blockade by Modified Bromage Scale and sensory blockade to 2 dermatomal levelsTimepoint: Upto 4 hours post-operatively