The Vascularity Changes of Scars With Laser Therapy
- Conditions
- Hypertrophic Scar
- Registration Number
- NCT03986346
- Lead Sponsor
- The Hong Kong Polytechnic University
- Brief Summary
The purpose of this study is to explore the effects of pulsed dye laser on managing scar vascularity and thickness.
- Detailed Description
The pulsed dye laser is increasingly used in clinical settings to manage scars and shows promising outcomes.The pulsed dye laser targets at micro-vascular structures in scar tissues. This study aims to explore the vascularity changes in scars with pulsed dye laser during the scar formation process.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
- scars caused by burn injury or related trauma;
- wound healing days over 3 weeks;
- days post injury less than 1 year;
- ability and willingness to comply with all the treatment and assessment procedures.
- history of steroid injection or graft surgery;
- history of keloid scarring;
- open wound or active infection;
- conditions that affect wound healing, such as diabetes mellitus.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method scar thickness 3 months Ultrasound measures scar thickness.
scar erythema 3 months Dermoscopy captures the scar photo and measures degrees of scar erythema.
scar blood flow 3 months Ultrasound measures blood flow in scar tissues
- Secondary Outcome Measures
Name Time Method patient and observer scar assessment scale (POSAS) 3 months The POSAS measures scar vascularity, pigmentation, pigmentation, thickness, relief, pliability and surface area. Every parameter ranges from 1 to 10, and higher score indicates worse scar performance in that parameter. The total score of POSAS is calculated by summing all the parameters' scores.
Trial Locations
- Locations (2)
Southwest Hospital
🇨🇳Chongqing, China
Prince of Wales Hospital
🇭🇰Hong Kong, Hong Kong
Southwest Hospital🇨🇳Chongqing, China