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Clinical Trials/NCT06236776
NCT06236776
Not yet recruiting
Not Applicable

Arrhythmia Assessment in Structural Cardiac Interventions Using Wearable ECG Monitoring: AWARE Registry

Yonsei University1 site in 1 country150 target enrollmentFebruary 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Atrial Septal Defect
Sponsor
Yonsei University
Enrollment
150
Locations
1
Primary Endpoint
Occurrence of atrial fibrillation
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

This study is a multi-center (Sinchon Severance hospital / Gangnam Severance hospital), prospective cohort observational study to patients who had undergone structural heart intervention including device closure for secundum type atrial septal defect or Patent foramen ovale. Transthoracic echocardiography will be performed before the procedure, immediately after, and at 6, 18, 30 months after the procedure. Wearable ECG monitoring (> 3 days) will be performed before the procedure or immediately after procedure. Demographic, laboratory, hemodynamic data during procedure, and non-invasive imaging dat are obtained.

Registry
clinicaltrials.gov
Start Date
February 2024
End Date
June 2028
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult ≥ 19 year-old
  • Patients who scheduled to perform percutaneous device closure for atrial septal defect or patent foramen ovale
  • Patients provided with the written, informed consent to participate in this study

Exclusion Criteria

  • Patients who had paroxysmal, persistent, or chronic AF
  • Life expectancy \< 12 months
  • Subject who the investigator deems inappropriate to participate in this study

Outcomes

Primary Outcomes

Occurrence of atrial fibrillation

Time Frame: 30 month

Occurrence of atrial fibrillation at Immediate post-operative, 18, and 30 month on wearable ECG monitoring

Secondary Outcomes

  • All cause-death(Immediate post-operative, 18 month , 30 month)
  • hospitalization for heart failure(Immediate post-operative, 18 month , 30 month)
  • new atrial tachycardia(Immediate post-operative, 18 month , 30 month)
  • high burden of APC/PVC (>15%)(Immediate post-operative, 18 month , 30 month)
  • new atrial fibrillation(Immediate post-operative, 18 month , 30 month)

Study Sites (1)

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