Short- and long-term effects of various anti-glaucomatous eye drops on the foveal avascular zone (FAZ)

Phase 4

Recruiting

• Conditions: H40.1; Primary open-angle glaucoma

• Registration Number: DRKS00028293
• Lead Sponsor: Dietrich-Bonhoeffer-KlinikumKlinik für Augenheilkunde

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Patients older than 21 years Patients' willingness to participate in the study and written informed consent.
-Diagnosis of primary chronic open-angle glaucoma, pseudoexfoliation glaucoma, ocular hypertension requiring treatment or pigment dispersion glaucoma

Exclusion Criteria

Patients with poor general condition or poor compliance
-Patients diagnosed with various eye disorders affecting the macular area
-Patients with an acute angle-closure situation
-Intravenous or oral ingestion of acetazolamide and/or mannitol

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination on the effect of the short-term effect of the eye drop application after 30 minutes and after 60 minutes on vessel density, area, circumference, circular shape of the foveal avascular zone using angio-OCT images

Secondary Outcome Measures

Name	Time	Method
ong-term effect (permanently minimized FAZ) of local anti-glaucomatous therapy on patients who needed a renewed tension profile after 6/12 months