A clinical trial to study the outcomes of two intraoperative fluid management strategies to guide fluid therapy in renal transplant recepient patients

Not yet recruiting

Lead Sponsor: Postgraduate institute of medical education and researchPGIMER Chandigarh

Brief Summary: This study is a randomized double blind controlled study to determine determine the ability of Pulse PressureVariation guided fluid therapy as an alternative to CVP guided fluid therapy inrenal transplant recipients by assessing the amount of fluid used in both groups and tissue perfusion by lactate levels in both the groups and urine output and dialysis requirement in both the groups

Recruitment & Eligibility

Inclusion Criteria

Patients with End Stage Renal Disease undergoing Renal Transplantation.

Exclusion Criteria

Active coronary artery disease or congestive heart failure Atrial fibrillation or flutter Valvular Heart Disease Significant pulmonary insufficiency.

Primary Outcome Measures

Name	Time	Method
To determine the ability of Pulse Pressure Variation guided fluid therapy as an alternative to CVP guided fluid therapy in renal transplant recipients by comparing the amount of fluid administered at the end of surgery	1 hour post op

Secondary Outcome Measures

Name	Time	Method
To compare adequacy of tissue perfusion at the end of surgery.To find out the total volume of fluid administered in two groups during surgery and in the	immediate post-operative period

Locations (1): Postgraduate institute of medical education and research, Chandigarh
🇮🇳
Chandigarh, CHANDIGARH, India
Postgraduate institute of medical education and research, Chandigarh
🇮🇳Chandigarh, CHANDIGARH, India
Dr Gowtham K
Principal investigator
8113857581
kgdx08@gmail.com