A clinical trial to study the effect of different doses of phenylephrine hydrochloride for treatment of fall in blood pressure during spinal anaesthesia in patients undergoing emergency caesarean section for compromised fetus
Phase 4
Suspended
- Conditions
- Health Condition 1: null- Spinal anaesthesia induced hypotension
- Registration Number
- CTRI/2012/01/002330
- Lead Sponsor
- niversity College of Medical Sciences and Guru Teg Bahadur Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
ASA I or II females with singleton pregnancy undergoing emergency LSCS under spinal anaesthesia due to compromised status of the foetus (foetal distress)
Patients who develop hypotension after subarachnoid block will be included
Hypotension after spinal anaesthesia will be defined as systolic blood pressure less than 100 mm Hg
Exclusion Criteria
• Maternal complications e.g. diabetes, pregnancy induced hypertension, cardiovascular disease, cerebrovascular disease
• Patients with absolute or relative contra-indications for spinal anaesthesia e.g.infection in lumbar area, coagulation abnormalities, autonomic neuropathy, spinal deformities, other neurological diseases, hypovolemia due to any cause
• Maternal baseline SBP less than 100 mmHg
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method mbilical arterial pH, Incidence of foetal acidosis, <br/ ><br>APGAR scores <br/ ><br> <br/ ><br>Efficacy to treat post-spinal hypotension <br/ ><br>Timepoint: After delivery <br/ ><br>
- Secondary Outcome Measures
Name Time Method Maternal complications, if any <br/ ><br> <br/ ><br>Incidence of bradycardia <br/ ><br> <br/ ><br>Timepoint: During study period i.e. till the time of delivery of baby