High fibre diet and low dose lincomycin for chronic constipatio

Completed

• Conditions: Chronic constipation; Digestive System; Constipation

• Registration Number: ISRCTN33023013
• Lead Sponsor: Institute of Gastroenterology (Instituto de Gastroenterologia) (Argentina)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02-16
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Meet Rome II diagnostic criteria for chronic constipation characterised by:
1.1. A frequency of less than or equal to two bowel movements/week
1.2. Hard stool
1.3. Straining with occasional pain in more than 25% of bowel movements
2. Aged over 18 years, either sex

Exclusion Criteria

1. Cardiac, pulmonary, renal, liver failure
2. Abnormal blood chemistries
3. Known antibiotic allergies

In patients who were younger than 50 years and had no other complaint than chronic constipation and the physical examination and routine body chemistries were normal, it was assumed the diagnostic of functional constipation and no special gastrointestinal exams were performed. Patients greater than or equal to 50 years or with lower gastrointestinal bleeding underwent colon radiology or colonoscopy to rule out organic colorectal disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference between treatments in the mean bowel frequency, straining, stool consistency and pain during defecation at baseline (Day 0) and by the end of treatment period (Day 21).

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures