Study on evaluation of a tool named perfusion index to assess effectiveness of pain medication dexmedetomidine in reducing pain during laparoscopic gall bladder removal surgery under general anaesthesia

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/11/060025

Lead Sponsor: Amala Institute of Medical Sciences

Brief Summary: Quantifying nociception under anaesthesia is difficult and therefore reaction to nociception is used for monitoring through increased sympathetic activity or the corresponding decreased sympathetic stimulation

In any way surgical procedures as far as an anaesthetist is concerned in providing pain free journey is most important. So to identify nociceptive condition as fast as possible via an effective simple reliable tool is important. The usual parameters we use for pain assessment is heart rate, blood pressure variation and in this study we are assessing whether perfusion index can assess the nociceptive changes in surgery in an effective and reliable way.

In this study we mainly aim at comparing the parameters used for assessing pain like heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure along with variations of perfusion index in patients receiving dexmedetomidine infusion intra operatively and patients receiving conventional anaesthesia for laparoscopic cholecystectomy procedures.

After meeting inclusion and exclusion criteria a total number of 60 patients will be recruited for this longitudinal study in a consecutive sampling manner.

Primary objective of study is to compare the variation in perfusion index in response to pain stimulus and variability of perfusion index in subsequent pain stimulus after intravenous administration of dexmedetomidine during laparoscopic cholecystectomy surgeries under General anaesthesia and to compare the perfusion index with hemodynamic parameters such as heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure with or without dexmedetomidine

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Physical state ASA 1-2 Age group 18 years to 70 years Patients undergoing elective laparoscopic cholecystectomy surgeries under General anaesthesia.

Exclusion Criteria

Patients not willing to participate in this study History of allergy to the drugs in the study Patients with neurological or psychiatric illness,chronic pain disorder.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome - incidence and severity of intra-op pain stimulus assessed using perfusion index tool	Before induction,after induction,after intubation,1,2,3,2,4,6,8,10,15,20,25,30 minutes

Secondary Outcome Measures

Name	Time	Method
Comparison of perfusion index with hemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure	Before induction, after induction, after intubation,1,2,3,2,4,6,8,10,15,20,25,30 minutes

Trial Locations

Locations (1): Amala Institute of Medical Sciences
🇮🇳
Thrissur, KERALA, India
Amala Institute of Medical Sciences
🇮🇳Thrissur, KERALA, India
Dr Sarath BabuPD
Principal investigator
8547327875
sarathbabupd93@gmail.com