NCT04798976Unknown不适用
Personalized Evidence-based Treatment Improves Survival in Patients With Invasive Breast Cancer
Center of Personalized Medicine, Pirogova1 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2021年3月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- The percentage of guideline-consistent and personalized EBM recommendations
研究概览
简要总结
A population-based case-cohort study of breast cancer-specific survival among all first invasive breast cancer cases
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 70 Years（Child, Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All women with stage I-III disease who survived at least 12 months post-diagnosis
排除标准
- •Unknown cause of death Treatment outside the region (thus precluding the treatment assessment)
研究组 & 干预措施
CDSS (MedicBK) Analysis
干预措施: neoadjuvant/adjuvant therapy (Drug)
Core Laboratory Analysis
干预措施: neoadjuvant/adjuvant therapy (Drug)
结局指标
主要结局
The percentage of guideline-consistent and personalized EBM recommendations
时间窗: 3-year
The percentage of guideline-consistent and personalized EBM recommendations acted on by clinicians in patients with first invasive breast cancer. All discrepancies between routine and CDSS-recommended treatment resulting in frame of guideline-consistent therapy and personalized EBM therapy will be adjudicated by core laboratory.
次要结局
- Breast cancer-specific survival(3-year)
- Quantify the performance of the CDSS (MedicBK) algorithm(3-year)
- Predictors(3-year)
研究者
Evgeny Pokushalov
Director for research and development
Center of Personalized Medicine, Pirogova
研究点 (1)
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