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临床试验/NCT04520763
NCT04520763已完成不适用

Effects of Respiratory Muscle Exercises on Glucose Tolerance in Healthy Adults

Swiss Federal Institute of Technology2 个研究点 分布在 1 个国家目标入组 42 人开始时间: 2020年8月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
42
试验地点
2
主要终点
Peak blood glucose concentration

研究概览

简要总结

To evaluate the acute effects of respiratory muscle exercises vs. a control intervention on blood glucose kinetics in healthy adults after an oral glucose tolerance test.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥18 years
  • Non-smoking
  • Body mass index (BMI): 18.5 - 29.9 kg∙m-2
  • Normal lung function
  • Willing to adhere to study rules

排除标准

  • Known or suspected non-compliance, drug or alcohol abuse
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant
  • Previous enrolment into the current study
  • Intake of medications affecting metabolism, the cardiovascular or the respiratory system, or sleep
  • Acute illness or chronic conditions of the gastrointestinal tract, and health conditions affecting metabolism, the cardiovascular or the respiratory system, or sleep
  • Pregnancy, breastfeeding, or intention to become pregnant during the study

结局指标

主要结局

Peak blood glucose concentration

时间窗: throughout the study, an expected average of 2 weeks per participant

Peak blood glucose concentration will be determined in the three conditions (5min or 15min respiratory muscle exercises or control).

area under the glucose-time curve

时间窗: throughout the study, an expected average of 2 weeks per participant

Area under the glucose-time curve will be determined in the three conditions (5min or 15min respiratory muscle exercises or control).

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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