Investigating the Effects of Orienting Skin Grafts Parallel to Skin Tension Lines on Quality of Life in Head and Neck Located Basal Cell Carcinoma

Completed

• Conditions: Basal Cell Cancer; Grafting

• Registration Number: NCT06894056
• Lead Sponsor: Sifa Okulu - Independent Research Center of Dermatology and Venereology

Brief Summary

The goal of this observational study is to learn about the effect of orienting graft for treatment of skin cancer in patients who undergo skin cancer excision and grafting for their skin cancer. The main question to answer is

Does orienting the grafts parallel with skin tension lines have any effect on quality of life or cosmetic results?

Participants who already underwent or planned to undergo an excision and grafting procedure will answer a qaulity of life tool and cosmetic results will be evaluated by two seperate dermatologist.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-20
• Primary Completion: 2025-02-22
• Study Completion: 2025-02-22
• Status Verified: 2025-03
• Study First Submitted: 2025-03-17
• Study First Submitted QC: 2025-03-23
• Last Update Submitted: 2025-03-23
• Study First Posted: 2025-03-25
• Last Update Posted: 2025-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

• Patients with nodular basal cell carcinomas with a tumor size equal or less than 12 millimeters
• A history of surgical excision and grafting

Exclusion Criteria

• Immunosuppressed patients
• Recurrent tumors
• Patients with BCC's that arose from the previously irradiated area
• Gorlin's Syndrome diagnosis
• Illiterate individuals
• İmpaired cognitive functions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of Life Outcome	At least three months after surgery and grafting	Quality of life outcome was measured by the disease specific tool "Skin Cancer Quality of Life Impact Tool", SCQOLIT is a 10 item questionnaire and each item has 4 answers, total score is ranged between 0-30. Higher scores mean worse outcomes.
Quality of Life - General	At least three months after surgery and grafting	Dermatology Quality of Life Index was also used to evaluate quality of life as a general quality of life tool. DLQI is alsa a ten item tool with a total score range between 0-30. Higher scores mean worse outcomes.

Secondary Outcome Measures

Name	Time	Method
Cosmetic Outcome	At least three months after the surgery and grafting	Cosmetic outcome of the grafting at the third month, evaluated by two different dermatologists one of whom did the operations. As the initial part of the study was during pandemic precautional period second surgeon the results via photographs (teleconsultation). Visual analog scala is used, the scale is ranged between 0-8, higher scores meaning better outcomes.

Trial Locations

Locations (1)

Dr. Hilayda Karakök Deri ve Zührevi Hastalıklar Muayenehanesi; 🇹🇷 Ordu, Turkey