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Clinical Trials/NCT02551146
NCT02551146
Terminated
N/A

Influence of Implants and Locators for Improved Retention of Mandibular Full Dentures on Patient's Quality of Life and Oral Function. A Controlled, Randomized and Prospective Study

Philipps University Marburg Medical Center1 site in 1 country14 target enrollmentSeptember 7, 2015

Overview

Phase
N/A
Intervention
Not specified
Conditions
Mouth, Edentulous
Sponsor
Philipps University Marburg Medical Center
Enrollment
14
Locations
1
Primary Endpoint
Quality of life (OHIP-G-49)
Status
Terminated
Last Updated
3 years ago

Overview

Brief Summary

The aim of this study is to assess the influence of this particular treatment method on the patients' quality of life and masticatory function.

Detailed Description

For this prospective randomized controlled clinical trial patients with edentulous mandibles and tissue supported (full) dentures were treated with 2 dental implants and locators in order to improve prosthesis stability. The LOCATOR System is comprised of three parts: The LOCATOR implant attachment (LOCATOR abutment), the LOCATOR Male and the LOCATOR Denture Cap. The abutment is inserted directly into the implant using a torque wrench, while the Denture Cap is placed into the base of the overdenture for polymerization using acrylic resin. Custom retention is achieved via LOCATOR Males - small color-coded (according to retention force) plastic inserts - which can be exchanged as needed.

Registry
clinicaltrials.gov
Start Date
September 7, 2015
End Date
May 17, 2018
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • age 45-80 years (male or female)
  • sufficient full dentures in the mandible
  • must be able to clean their teeth on their own
  • edentulous mandible with interforaminal adequate bone for insertion of implants
  • implantation sites free of infections and root fragments
  • no need for treatment of the maxillary teeth
  • Written Informed Consent

Exclusion Criteria

  • systemic diseases
  • mental disability that may affect the participant's ability to properly follow study instructions
  • oral mucosal diseases
  • long-term medication with steroids, bisphosphonates
  • known allergic reactions to dental materials
  • malignant tumor in the head and neck area
  • requirement of any concurrent radiotherapy or chemotherapy or any radiotherapy or chemotherapy within the last 10 years pregnancy or breastfeeding at study entry

Outcomes

Primary Outcomes

Quality of life (OHIP-G-49)

Time Frame: 3 months after randomization

The oral health-related quality of life is assessed by the German version of the Oral Health Impact Profile questionnaire (OHIP-G-49, Locker et al 1993)

Secondary Outcomes

  • Mucosal recessions(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • width of keratinized gingiva/mucosa(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • Gingival index(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • intraoral photo-documentation(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • masticatory function(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • Plaque index(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • Probing pocket depth(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))
  • Gingival recessions(3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3))

Study Sites (1)

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