Feasibility of high-intensity interval training with hyperoxia in cancer patients undergoing chemotherapy

Not Applicable

Recruiting

• Conditions: all carcinoma (except for lung carcinoma); C00-C97; Malignant neoplasms

• Registration Number: DRKS00011689
• Lead Sponsor: Deutsche Sporthochschule Köln, Institut für Kreislaufforschung und Sportmedizin, Abt.2: Molekulare und Zelluläre Sportmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Men with carcinoma undergoing chemotherapy as an adjuvant or primary therapy

Patients treated with conventional chemotherapy:
- Alkylating agents
- Antimetabolites
- Anthracyclines
- Taxanes
- Vincaalcaloides
- Patients treated with antibody therapy

Exclusion Criteria

- Patients with lung-ca
- Relapsed carcinoma
- Recent serious cardiovascular events (including but not limited to poorly controlled hypertension and congestive heart failure)
- Medical condition such as uncontrolled infection or cardiac disease that, in the opinion of the physician, would make this protocol unreasonably hazardous for the patient
- Psychiatric illness, which would prevent the patient from giving informed consent or adhering to the study protocol
- Known spinal cord compromise or instrumentation due to metastatic disease. Radiation therapy for metastatic disease is allowed
- Peripheral neuropathy
- Men participating in vigorous aerobic exercise for more than 60 minutes per week or resistance exercise two or more days per week
- shortness of breath, chest discomfort, or palpitations when performing activities of daily living
- Men having difficulties of climbing a flight of stairs due to physical impairment
- Ongoing restriction of physical activity with physician documentation
- chest pain brought on by physical activity and chest pain developed in the past month
- Patients with carcinoma which limit physical exercise on a bike ergometer

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility and compliance assessed by the following questionnaires (at baseline and after 4 weeks of training):<br><br>BPI-SF (Brief Pain Inventory - Short Form)<br>FACIT-F (Functional Assessment of Chronic Illness Therapy - Fatigue)<br>FACIT-TS-G (Functional Assessment of Chronic Illness Therapy - Treatment rating)<br>PSQI (Pittsburgh Sleep Quality Index)<br><br>Immune status assessed by venous blood analyses (at baseline and after 4 weeks of training).