Corneal Endothelium Morphology and Central Thickness in Type II Diabetes Mellitus and Normal Subjects
- Conditions
- Corneal Dystrophy
- Registration Number
- NCT01084850
- Lead Sponsor
- Frederiksberg University Hospital
- Brief Summary
The purpose of this study is to compare corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with special reference to glycemic status.
- Detailed Description
Diabetes might influence the health of the corneal endothelium. Older studies have presented different results and the glycemic status of the patients have not been reported. In this study we examine the corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with modern specular microscopy. Each patient and control is examined once ("entry to study").
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
- Type II diabetes (diagnose confirmed by general practitioner)
- Controls with no diabetes (confirmed by blood testing).
- Glaucoma
- Uveitis (current or previous)
- Corneal scaring
- Previous eye surgery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Corneal endothelium cell number 1 year The study is a cross-sectional study. We compare a cohort of patients with DM to a cohort with no DM. We examine each patient and control once. We call time of appointment or examination for "at entry to study".
- Secondary Outcome Measures
Name Time Method Corneal endothelium morphology 1 year The size and hexagonality of the cells are analysed automaticly by computer recognizion.
Trial Locations
- Locations (1)
Frederiksberg University Eye Clinque
🇩🇰Frederiksberg, Denmark