Predictability of Neonatal Lung Ultrasound Score in preterm neonates with respiratory distress

Not yet recruiting

Conditions: Respiratory distress syndrome of newborn,

Registration Number: CTRI/2024/05/067214

Lead Sponsor: K S Sivakumar

Brief Summary: 1.Neonatal lung ultrasound has become an indispensable bedside tool in Neonatology in recent years as it is quick, radiation-free, minimally invasive and holds the characteristics of a point-of-care technique.

2. A lung ultrasound can be used to easily diagnose respiratory distress syndrome, and a semiquantitative score based on ultrasound findings may reveal lung aeration.

3. The objective of our study is to assess the diagnostic accuracy of a neonatal-adapted LUS score to evaluate the need for surfactant administration in preterm neonates with respiratory distress.

4.Now Fio2 requirement is the main factor for deciding surfactant need as per European consensus guideline 2019. By assessing ultrasound score and comparing with Fio2 requirement lung ultrasound score can be used as primary diagnostic in future NICU.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

All preterm neonates born at <34 weeks of gestation with respiratory distress and requiring some form of respiratory support (mechanical ventilation, continuous positive airway pressure, high flow humidified nasal cannula) to maintain target blood oxygen saturation levels and admitted within 48 hours of life will be enrolled in the study group after informed consent from the parents/ guardians.

Exclusion Criteria

Neonates with 1.Chromosomal abnormalities or complex congenital malformations 2.
Congenital lung diseases 3.
Neonates with surgical comorbidities 4.
Congenital heart defects 5.
Delivery room surfactant administration.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the accuracy of Lung Ultrasound Score in preterm neonates with respiratory distress in predicting the need for surfactant therapy based on European Consensus Guidelines on the Management of Respiratory Distress Syndrome	6hours, 12 hours, 18hours and 24 hours of surfactant administration.

Secondary Outcome Measures

Name	Time	Method
1. To predict need for surfactant retreatment based on initial & subsequent LUS score	2.To assess the diagnostic accuracy of LUS for RDS in different gestational age groups

Trial Locations

Locations (1): Dr.Mehtas hospital
🇮🇳
Chennai, TAMIL NADU, India
Dr.Mehtas hospital
🇮🇳Chennai, TAMIL NADU, India
Dr K S Sivakumar
Principal investigator
9600062062
k.s.sivakumar85@gmail.com