Remote Ischemic Preconditioning in Cardiac Surgery

Not Applicable

• Conditions: Ischemia Reperfusion Injury
• Interventions: Procedure: Sham remote ischemic preconditioning; Procedure: remote ischemic preconditioning

• Registration Number: NCT04647370
• Lead Sponsor: Assiut University

Brief Summary

Aim of the work :

Evaluation of the role of Remote Ischemic Preconditioning (RIP) on liver function in patients undergoing on-pump cardiac surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-09-27
• Study First Submitted QC: 2020-11-26
• Study First Posted: 2020-11-30
• Status Verified: 2021-04
• Study Start: 2021-04-01
• Last Update Submitted: 2021-04-16
• Last Update Posted: 2021-04-20
• Primary Completion: 2022-01
• Study Completion: 2022-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1. Being candidate for on-pump cardiac surgery.
2. Willing to participate in the study
3. Ages eligible for the study: 18 to 70 years.
4. Gender eligible for the study : both

Exclusion Criteria

1. Patient refusal.
2. Known cause of possible liver function disturbances that includes right heart failure, acute inflammation of gallbladder or any other complication of gallstone disease.
3. Active viral and non viral hepatitis.
4. Pregnant women.
5. History of peripheral nerve disease or peripheral vascular disease of the extremities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Sham remote ischemic preconditioning	Sham remote ischemic preconditioning	-
Remote ischemic preconditioning	remote ischemic preconditioning	-

Primary Outcome Measures

Name	Time	Method
liver function test	3 postoperative days	Direct Bilirubin

Trial Locations

Locations (1)

Assiut University hospital; 🇪🇬 Assiut, Asyut Governorate, Egypt