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Clinical Trials/NCT00611611
NCT00611611CompletedNot Applicable

BLyS and IFN Responses to Antigen Challenge in Human SLE

University of Alabama at Birmingham1 site in 1 country39 target enrollmentStarted: October 2007Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
39
Locations
1
Primary Endpoint
change in specific antibodies in response to vaccine
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This protocol tests whether changes in BLyS or IFN can be detected in a normal immune response to a vaccine and, if so, whether the response differs between those with lupus and healthy controls.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
19 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •ACR lupus criteria
  • •18<age<65

Exclusion Criteria

  • •chronic infection or cancer
  • •pregnancy

Outcomes

Primary Outcomes

change in specific antibodies in response to vaccine

Time Frame: 2 weeks

Secondary Outcomes

  • change in BLyS after vaccination(2 weeks)
  • change in IFN after vaccination(2 weeks)

Investigators

Sponsor Class
Other

Study Sites (1)

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