ITMCTR2000003312招募中1 期
Treatment of knee osteoarthritis with small needle knife: a randomized controlled trial
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 40 至 80（—）
- 性别
- All
入选标准
- •1. Patients who meet the stage I, II, III of Kellgren-Lawrecne's radiological diagnostic criteria;
- •2. KAS pain VAS score >= 4 points;
- •3. The age is between 40-70 years old, regardless of gender;
- •4. Those who have not taken other related treatment drugs or adopted related treatment measures within 2 weeks;
- •5. Participate voluntarily, sign the informed consent form, be willing to accept the trial, and follow the random grouping.
排除标准
- •1. Women who are pregnant or breastfeeding, or who have a pregnancy plan during the trial;
- •2. Patients with severely life-threatening cardiovascular and cerebrovascular diseases, liver, kidney, hematopoietic system and other diseases or infectious diseases, who are unable to complete or are not suitable for related treatment and examination;
- •3. Patients with local infection, ulceration, vascular nerve injury or deep abscess in the knee;
- •4. Patients who have a history of severe knee trauma, or have undergone surgery or arthroscopy treatment;
- •5. Patients with other bone diseases such as tuberculosis, tumors, rheumatism, rheumatoid arthritis, gouty arthritis and other bone diseases that are not osteoarthritis or knee pain caused by other diseases;
- •6. Patients who have received oral hormonal drugs or knee closure therapy and other interventions within 1 month; or patients who have participated in other clinical trials within 3 months;
- •7. People who are allergic to the medical devices involved in this trial; contraindications to the use of indomethacin plaster, such as those with a history of allergy to indomethacin, those with liver and kidney dysfunction (alanine aminotransferase (ALT), aspart The amino acid transaminase (AST) is more than 2 times the normal value, and the blood creatinine (cr) is more than the normal value). Patients who have induced asthma, urticaria or allergic reactions after taking aspirin or other non-steroidal anti-inflammatory drugs may have nonsteroidal Patients with a history of gastrointestinal bleeding or perforation after anti-inflammatory drugs, patients with active gastrointestinal ulcer bleeding, or patients with previous recurrent ulcers / bleeds, patients with severe heart failure, perioperative coronary artery bypass surgery, etc .;
- •8. Patients with bleeding tendency, such as long-term use of anticoagulants such as warfarin and aspirin;
- •9. Those who have a history of sedative hypnotics, opioid analgesics and alcohol abuse;
- •10. Patients with cognitive impairment, or language communication impairment, unable to express accurately.
研究者
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