The Effect of Caffeine in Elderly Citizens

Phase 4

Completed

• Conditions: Healthy Elderly Citizens

• Registration Number: NCT00117520
• Lead Sponsor: Herning Hospital

Brief Summary

The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years. The main hypothesis was that 6 mg/kg caffeine would improve cycling endurance at 65% of expected maximal heart rate.

Detailed Description

Caffeine ingestion increases the endurance of young people exercising at 60%-85% of their maximal oxygen uptake, and it also seems to improve endurance as measured by repeated sub-maximal isometric contraction and decreases the rate of perceived exertion during exercise. Although caffeine increases endurance in young people, an increase in endurance may be of greater interest in the elderly as the population of older adults with a physically active lifestyle is growing rapidly or for increasing endurance fitness through an exercise or rehabilitation program. Therefore the main hypothesis was that caffeine would improve cycling endurance at 65% of expected maximal heart rate, and the secondary hypotheses were that caffeine would improve postural stability, reaction and movement times, isometric arm flexion endurance, and walking speed, and would reduce the rate of perceived exertion after 5 minutes of cycling in healthy elderly citizens.

Study Timeline

• Status Verified: 2002-07
• Study Start: 2002-07
• Study First Submitted: 2005-06-30
• Study First Submitted QC: 2005-06-30
• Study First Posted: 2005-07-07
• Study Completion: 2006-03
• Last Update Submitted: 2006-07-03
• Last Update Posted: 2006-07-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Healthy elderly individuals aged over 70 years

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Exclusion Criteria

• Dementia or invalidating psychiatric disease
• General debility, angina, or other diseases that would render participation in the test program impossible
• Treatment with beta receptor blocking drugs, calcium-channel blocking drugs, digitalis, or nitroglycerine
• Acute disease and injury
• Diabetes
• Conditions that would contraindicate caffeine ingestion or participation in the test program
• Treatment with medication that interacts with caffeine
• Ingestion of caffeine containing drinks and foods 48 hours before each session

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
endurance measured on an ergometer bicycle

Secondary Outcome Measures

Name	Time	Method
postural stability
reactiontime
isometric endurance (armflexion)
walking speed
fatigue

Trial Locations

Locations (1)

Surgical Research Department; 🇩🇰 Herning, Ringkjoebing, Denmark