Intralesional microinjection of tranexamic acid for treatment of hyperpigmented skin grafts

Phase 3

Completed

• Conditions: Hyperpigmented Skin Grafts; Tranexamic Acid; Hyperpigmented Skin Grafts&#44

• Registration Number: TCTR20180622001
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-11-29
• Study Start: 2018-06-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

Hyperpigmentation of STSG
Procedure <1 yr
Wound completely healed
Size 18 cm2 - 48 cm2 (Limited by maximum dose of TXA)
Age 18 - 60 years old

Exclusion Criteria

Concurrent use of whitening agent within 1 month before their entry into the study
Pregnant , lactating mother
Contraceptive pills at the time of the study or during the past year
Inadequate follow-up

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
melanin index 4 week, 8 week, 12 week, 6 month Skin colorimeter

Secondary Outcome Measures

Name	Time	Method
decrease hyperpigmentation 6 month Patient-rated