NCT04118816Unknown不适用
Impact of Sleep-disordered Breathing on Autonomic Regulation in Patients With Prader-Willi Syndrome
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2019年6月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Narcolepsy prevalence
研究概览
简要总结
To evaluate autonomic regulation in patients with Prader-Willi syndrome with sleep-disordered breathing.
详细描述
To evaluate the relationship between narcolepsy and sleep-disordered breathing, the natural course of untreated or treated sleep-disordered breathing and its impacts on autonomic regulation in patients with Prader-Willi syndrome with sleep-disordered breathing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 7 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •7-75 y/o Prader-Willi syndrome patients or healthy subjects
- •can perform polysomnography, multiple sleep latency test
- •orthostatic methods for autonomic function test
- •can perform pulmonary function test.
排除标准
- •less than y/o, or larger then 75 y/o
- •cannot perform polysomnography, multiple sleep latency test
- •cannot orthostatic methods for autonomic function test
- •cannot perform pulmonary function test
- •use of sedatives or drugs affecting autonomic function
结局指标
主要结局
Narcolepsy prevalence
时间窗: 1day
Compare the narcolepsy prevalence amount healthy and Prader-Willi syndrome with or without sleep-disordered breathing
次要结局
- The natural course and its impact of untreated sleep-disordered breathing on autonomic regulation in patients with Prader-Willi syndrome.(12 months)
研究者
研究点 (1)
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