Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Adenomas per colonoscopy
研究概览
简要总结
Narrow band imaging or electronic chromoendoscopy might provide similar adenoma detection capabilities while limiting time spent when compared to conventional chromoendoscopy method.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Single (Participant)
盲法说明
Randomization cards will be sealed and opened after the subject is deemed eligible for the study by the PI. This will be done in an area away from the subject but due to the nature of the study, PI can't be blinded.
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 40 years
- •Referral for screening, surveillance or diagnostic colonoscopy
排除标准
- •Inflammatory bowel disease
- •History of colorectal cancer or colon resection
- •Indication of positive FIT or cologuard
- •Any colorectal cancer syndromes (FAP, HNPCC, SPS)
- •Patient with poor bowel preparation identified during insertion
研究组 & 干预措施
High definition white light endoscopy
colonoscopy performed using high definition equipment
干预措施: High definition white light endoscopy (Other)
Chromoendoscopy
indigo carmine is sprayed on the colon mucosa during withdrawal phase
干预措施: Chromoendoscopy (Other)
Narrow band imaging
Narrow band imaging is used during withdrawal phase
干预措施: Narrow band imaging (Device)
结局指标
主要结局
Adenomas per colonoscopy
时间窗: during the procedure
total number of adenomas divided by total number of procedures
次要结局
- Sessile serrated polyp detection rate(during the procedure)
- Sessile serrated polyps per colonoscopy(during the procedure)
- Adenoma detection rate(during the procedure)
- Withdrawal time(during the procedure)
- Inspection time(during the procedure)
研究者
Douglas K. Rex
Emeritus Professor of Medicine
Indiana University