Diode Laser and Red Complex Periodontal Bacteria

Phase 2

• Conditions: Oral Health

• Registration Number: PACTR201909915338276
• Lead Sponsor: Dr Sune Mulder van Staden

Brief Summary

http://hdl.handle.net/11394/5609 Evaluation of the results demonstrated that the diode laser produced no statistical decrease in the bacterial parameters in the periodontal pockets and resulted in a statistical increase of C. showae (Cs) and T. denticola (Td). The clinical parameters resulted in no statistical difference for any clinical parameter, with the exception of the reduction in BOP that was statistically significant (p< 0,05) with the laser as an adjunct. It is the recommendation that within the limitations of this study, that the utilization of the diode laser (810 ± 10nm) as an adjunct at the initial visit had no statistical effect in the reduction of the bacterial parameters nor resulted in an overall improvement of the clinical parameters.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-20
• Results First Posted: 2019-12-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

The participants had to be adult patients (over the age of 18 years-64 years). For the purpose of this study the participants were diagnosed with chronic periodontitis and had to present with a minimum of four teeth present per quadrant. At least three teeth per quadrant had to present with periodontal probing pocket depths of 5mm or more in any of the six point probing areas namely mesio-buccal (MB), buccal (B), disto-buccal (DB), mesio-palatal (MP), palatal (P), disto-palatal (DP) per tooth were assessed.

Clinical features defining a diagnosis of chronic periodontitis:

Oedema and tissue erythema

Moderate accumulations of plaque and calculus

Bleeding on probing (BOP)

Increased pocket depths (minimum probing pocket depth of 4mm)

Radiographic evidence of bone loss (angular or horizontal)

Tooth mobility
Varying degrees of clinical attachment loss

Slow to moderate rate of progression

Amount of destruction consistent with the presence of local factors – such as plaque and calculus.
The chronic periodontitis could have presented as localised (<30% of sites affected) or generalized (>30% of sites affected). The severity of the chronic periodontitis could have presented as mild (CAL= 1-2mm), moderate (CAL=3-4mm) or severe (CAL > 5mm) (Lindhe, 2015:129). All the above mentioned variants of chronic periodontitis were included in this study.

Exclusion Criteria

Patients under 18 years and over 65 years. The only underlying medical conditions that were excluded were patients that were pregnant (or lactating) and patients undergoing radiation or chemotherapy.

Patients with oral pigmentation of the attached gingiva in the study area of interest were also excluded from the study, as pigments (such as melanin) absorb laser energy at varying amounts which could potentially have an effect on the results.

Patients who smoked more than 10 cigarettes per day were excluded.Patients that had taken antibiotics in the previous 6 months were excluded.Patients who had periodontal treatment in the previous 6 months were also excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bacterial determination and the change in the colony forming units.

Secondary Outcome Measures

Name	Time	Method
All patients receive the diode laser after 6 weeks if the diode laser adjuct reduced the red complex bacteria colony forming units.