Exploration of Cerebral Metabolism and Connectivity in Post Traumatic Stress Disorder (PTSD): Exploratory Study of Neurofunctional Modulation of Emotions by Music Therapy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stress Disorder, Post Traumatic
- Sponsor
- Institut de Recherche Biomedicale des Armees
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- change in PTSD symptoms
- Status
- Terminated
- Last Updated
- 3 years ago
Overview
Brief Summary
PTSD is a debilitating mental disorder that may develop after experiencing or witnessing a life-threatening event. With appropriate care, treatment efficiency is variable and around 20% of the patients do not respond to psychological treatment. Complementary treatments are needed.
as PTSD implied autonomic nervous system (ANS) dysfonction, complementary treatment focusing on ANS regulation, as welle as musicotherapy, may have an interest.
Detailed Description
The aim is to evaluate the impact of musicotherapy on PTSD symptoms, and severity using a RCT Symptoms will be evaluated using questionaires (PCL and quality of life) severity will be measured using neurological soft signs assessment, connectomic functions and ANS regulation
Investigators
Marion Trousselard
principal investigator
Institut de Recherche Biomedicale des Armees
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •neurological diseases
- •addiction
Outcomes
Primary Outcomes
change in PTSD symptoms
Time Frame: change from PTSD symptoms at two months and at six months
questionnaire Posttraumatic CheckList 5 (PCL5; threshold =33)
Secondary Outcomes
- change in neurological soft signs(change from neurological soft signs at two months and at six months)
- change in effective connectomic(change from effective connectomic at two months and at six months)
- Autonomous nervous system regulation(change from Autonomous nervous system regulation at two months and at six months)
- change in biological stress(change from biological stress at two months and at six months)