Neural and Behavioural Bases of Action Simulation

Not Applicable

Not yet recruiting

• Conditions: Healthy Participants

• Registration Number: NCT06836297
• Lead Sponsor: Université Catholique de Louvain

Brief Summary

The goal of this interventional study is to understand the neural and behavioural bases of action simulation and its links with action execution in healthy volunteers.

Hypotheses: Action simulation recruits neural networks that are largely similar to those activated by action execution, with some differences to avoid executing a movement while observing/imagining it.

Participants will be tested with TMS while doing motor imagery or action observation.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-02
• Study First Submitted: 2025-02-10
• Study First Submitted QC: 2025-02-17
• Last Update Submitted: 2025-02-17
• Study First Posted: 2025-02-20
• Last Update Posted: 2025-02-20
• Study Start: 2025-03-01
• Primary Completion: 2028-02-01
• Study Completion: 2028-02-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• healthy adult volunteers (more than 18 years old)

Exclusion Criteria

• Participants taking anti-epileptic drugs
• pregnant or breastfeeding women cannot participate in this study
• people with a pacemaker
• people with a cochlear implant
• people with a metal part in the brain or any other medical implant in their body (pump, neurostimulator, valve,) cannot take part in this study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Motor Evoked Potential (MEP)	For the duration of the participants' visit to the laboratory (max 2h30)	Evoked motor potentials will be measured throughout the experiment using surface electrodes on different muscles to measure changes in corticospinal excitability.