Neural and Behavioural Bases of Action Simulation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 300
- 主要终点
- Motor Evoked Potential (MEP)
研究概览
简要总结
The goal of this interventional study is to understand the neural and behavioural bases of action simulation and its links with action execution in healthy volunteers.
Hypotheses: Action simulation recruits neural networks that are largely similar to those activated by action execution, with some differences to avoid executing a movement while observing/imagining it.
Participants will be tested with TMS while doing motor imagery or action observation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy adult volunteers (more than 18 years old)
排除标准
- •Participants taking anti-epileptic drugs
- •pregnant or breastfeeding women cannot participate in this study
- •people with a pacemaker
- •people with a cochlear implant
- •people with a metal part in the brain or any other medical implant in their body (pump, neurostimulator, valve,) cannot take part in this study.
研究组 & 干预措施
Transcranial Magnetic Stimulation
For some experiments, all participants will take part in all experimental conditions. For other experiments, participants will be randomly assigned to different groups with different conditions (e.g. TMS sham vs. TMS test).
干预措施: Transcranial Magnetic Stimulation Sham (Device)
结局指标
主要结局
Motor Evoked Potential (MEP)
时间窗: For the duration of the participants' visit to the laboratory (max 2h30)
Evoked motor potentials will be measured throughout the experiment using surface electrodes on different muscles to measure changes in corticospinal excitability.
次要结局
未报告次要终点