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Studying Electromyographic Activity in Patients With Upper Limb Amputations

Not Applicable
Completed
Conditions
Amputation, Traumatic
Interventions
Other: Fine wire EMG electrodes
Registration Number
NCT02956603
Lead Sponsor
University of Michigan
Brief Summary

The primary purpose of this study is to determine the extent to which the Regenerative Peripheral Nerve Interface ( i.e. reinnervation of partial muscle grafts by residual peripheral nerves) enables both the generation of high-performance motor control signals for prosthetic limbs, and the input of sensory percepts by electrical stimulation.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
18
Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Neuroma GraftFine wire EMG electrodesIn this arm, participants have already had partial muscle grafts placed on the amputated nerves to control neuroma growth. The investigators will place small electrodes percutaneously into the muscle grafts to record EMG signals and electrically stimulate the implanted nerves.
Able BodiedFine wire EMG electrodesThe investigators will place small electrodes percutaneously into intact muscles in the arm to record EMG signals and electrically stimulate the intact nerves nearby.
Prosthetic Control GraftFine wire EMG electrodesIn this arm, participants will have an initial surgery to place partial muscle grafts on the amputated nerves. After a healing period, the investigators will place small electrodes percutaneously into the muscle grafts to record EMG signals and electrically stimulate the implanted nerves.
Primary Outcome Measures
NameTimeMethod
Amplitude of EMG signal<4 hours
Number of separate sensory percepts evoked<4 hours
Secondary Outcome Measures
NameTimeMethod
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