Development of plasma ghrelin level as a novel marker for risk stratification of gastric cancer
Not Applicable
- Conditions
- H. pylori-infected gastritis
- Registration Number
- JPRN-UMIN000014496
- Lead Sponsor
- Keio University
- Brief Summary
Total and acyl plasma ghrelin levels demonstrated no significant change from before treatment to 48 weeks after eradication; however, there was a significant difference between open-type and closed-type atrophic gastritis. The PG I/II ratio increased significantly from 48 weeks after H. pylori eradication. The severity of the histological intestinal metaplasia scores correlated inversely with plasma total ghrelin levels from before to 48 weeks after H. pylori eradication.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
Not provided
Exclusion Criteria
Patients after a laparotomy for the resection of esophagus or stomach
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of plasma ghrelin levels during the H. pylori eradication therapy
- Secondary Outcome Measures
Name Time Method