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临床试验/NCT04758663
NCT04758663Unknown不适用

The Role of Naps and Overnight Sleep on Cognitive Learning in Preschoolers

University of Massachusetts, Amherst1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2021年4月12日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
40
试验地点
1
主要终点
Overnight sleep physiology

研究概览

简要总结

The goal of this research is to understand the role of sleep on memory function in early childhood. Specifically, we seek to examine how promoted naps vs. promoted waking in habitual and non-habitual napping children may impact overnight sleep physiology and subsequent memory consolidation.

详细描述

With time spent awake, sleepiness increases (i.e., sleep pressure; Borbely, 1982). In young adults, naps following sleep deprivation have significantly elevated slow wave activity (SWA; 1-4 Hz) relative to naps following normal overnight sleep (Werth et al., 1996). Similarly in preschool children, overnight sleep following nap deprivation yields significantly greater SWS relative to when a nap was taken earlier in the day (Lassonde et al., 2016). This impact on subsequent sleep physiology suggests that naps may be an extension of overnight sleep. How napping status (i.e., habitual and non-habitual napping) impacts overnight sleep physiology and subsequent memory consolidation is unknown. Thus, this study aims to investigate how napping vs. staying awake in habitual and non-habitual napping children may impact overnight sleep physiology and subsequent memory consolidation.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

盲法说明

Within-subject; participants/experimenters are aware of conditions

入排标准

年龄范围
33 Months 至 71 Months(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Family lives within 30 miles of UMass Amherst
  • •Is 33-71 months at the time of enrollment
  • •Meets the definition of a habitual (5+ naps/week) or non-habitual (<2 naps/week) napper
  • •Normal or corrected-to-normal vision and hearing
  • •Access to a computer with an internet connection for online sessions with the research team.

排除标准

  • •Diagnosis of any sleep disorder (other than mild parasomnia which is routine at this age) past or present
  • •Current use of psychotropic or sleep-altering medications
  • •Traveling beyond 1 time zone within 1 month of participation
  • •Fever or symptoms of respiratory illness at the time of participation
  • •Diagnosed developmental disability

研究组 & 干预措施

Declarative memory

Experimental

Napping v. wake effect on declarative memory in habitual and non-habitual nappers.

干预措施: Nap/wake conditions on memory (Behavioral)

Overnight Physiology

Experimental

Napping v. wake effect on overnight physiology in habitual and non-habitual nappers.

干预措施: Nap/wake conditions on overnight physiology (Behavioral)

结局指标

主要结局

Overnight sleep physiology

时间窗: 9-11 hours of sleep overnight

Amount of slow wave activity and other non-REM sleep features in overnight sleep following a day where a nap was involved compared to when there was no nap earlier in the day.

次要结局

  • Change in memory accuracy(2-3 hours/24 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Rebecca Spencer

Associate Professor of Psychological and Brain Sciences

University of Massachusetts, Amherst

研究点 (1)

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