ACTRN12621000614897尚未招募4 期
Randomised controlled trial of the effect of two tapering regimens for withdrawal of glucocorticoids on pituitary-adrenal function recovery in patients taking supraphysiological glucocorticoid therapy
A/Prof W Inder - Investigator initiated0 个研究点目标入组 120 人开始时间: 2021年5月21日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Age 18 years or over
- •Able to give written informed consent
- •Medical condition which has required supraphysiological glucocorticoid therapy:
- •oPrednisolone dose (or equivalent) greater than or equal to 5 mg daily for 6 or more weeks
- •oDexamethasone greater than or equal to 0.5 mg daily for 6 or more weeks
- •Pre-dose morning cortisol <200 nmol/L
- •Managing clinician has clinical intent to cease glucocorticoids completely
排除标准
- •Condition requiring lifelong chronic glucocorticoid use
- •Known pathological pituitary or adrenal dysfunction
- •Active malignancy
研究者
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