Randomized Controlled Trials on Laparoscopic No. 14v Lymph Node Dissection for Advanced Lower Third Gastric Cancer

Brief Summary

Detailed Description

A prospective randomized comparison of laparoscopic No. 14v lymph node dissection in advanced lower third gastric cancer will be performed, to evaluate the short-term, long-term and oncological outcomes. The evaluation parameters are perioperative clinical efficacy, postoperative life quality, immune function and 3-year survival and recurrence rates.

Primary Outcomes

Secondary Outcomes

• No.14v Lymph node metastasis rate(10 days)
• Time to soft diet(10 days)
• 3-year free survival rate(36 months)
• The variation of weight(12 months)
• Time to first liquid diet(10 days)
• Morbidity and mortality(30 days; 36 months)
• 3-year recurrence pattern(36 months)
• Duration of hospital stay(10 days)
• The variation of albumin(12 months)
• The values of white blood cell count(7 days)
• The values of hemoglobin(7 days)
• Time to first ambulation(10 days)
• The number of lymph node dissection(10day)
• The daily highest body temperature(7 day)
• Time to first flatus(10 days)
• The amount of abdominal drainage(10 days)
• Intraoperative lymph node dissection time(1 day)
• The amount of use of titanium clip(1 day)
• The rate of conversion to laparotomy(1 day)
• The variation of cholesterol(12 months)
• The results of endoscopy(12 months)
• Visual Analog Score for pain(7 days)
• EORTC QLQ-C30 and QLQ - STO22(Time Frame: 36 months)
• Blood transfusion(10 days)
• The number of positive lymph nodes(1 day)
• Intraoperative blood loss(1 day)
• Intraoperative injury(1 day)
• The values of C-reactive protein(7 days)
• The values of relevant immune cytokines(7 days)
• The values of prealbumin(7 days)