Inpatient Blood Glucose Control in Taichung Veterans General Hospital

Phase 4

Recruiting

• Conditions: HYPERGLYCEMIA
• Interventions: Device: CONTINUE GLUCOSE MONITOR; Procedure: Insulin protocal

• Registration Number: NCT02885909
• Lead Sponsor: Taichung Veterans General Hospital

Brief Summary

This study will be conducted in the ward of Taichung Veterans General Hospital. The patient with hyperglycemia in hospitalization will be enrolled by glucose management team.

Detailed Description

This study will be conducted in the ward of Taichung Veterans General Hospital. The type 2 diabetic patient with hyperglycemia in hospitalization are candidates. The glucose will be controlled using the insulin protocal based on the glucose monitor systems. We will assess the effects of insulin protocal and glucose monitor system on the inpatient with hyperglycemia.

Study Timeline

• Study First Submitted: 2016-08-26
• Study First Submitted QC: 2016-08-26
• Study Start: 2016-09
• Study First Posted: 2016-09-01
• Status Verified: 2019-12
• Last Update Submitted: 2020-01-04
• Last Update Posted: 2020-01-07
• Primary Completion: 2022-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

• Type 2 diabetic inpatient
• Fasting glucose >140 mg/dl or random glucose >180 mg/dl

Exclusion Criteria

• incooperative for glucose monitor
• refusal of insulin
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Insulin protocal with CGM	CONTINUE GLUCOSE MONITOR	Insulin protocal with continue glucose monitor
Insulin protocal with CGM	Insulin protocal	Insulin protocal with continue glucose monitor
Insulin protocal	Insulin protocal	Insulin protocal with convential glucose monitor

Primary Outcome Measures

Name	Time	Method
Glucose target	6 days	The ratio of glucose less than 180 mg/dl

Secondary Outcome Measures

Name	Time	Method
Vascular Cell Adhesion Molecule 1 (VCAM-1)	6 days	Inflammation
Brain-Derived Neurotrophic Factor (BDNF)	6 days	Psychological assessment
Fasting glucose target	6 days	the ratio of fasting glucose less than 140 mg/dl
Hypoglycemia	times	symptoms or less than 70
Orexin-A	6 days	Psychological assessment

Trial Locations

Locations (1)

Taichung Veterans General Hospital; 🇨🇳 Taichung, Taiwan