In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

Not Applicable

Completed

• Conditions: Diabetes; Hyperglycemia

• Registration Number: NCT00302874
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.

The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.

Study Information:

* All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study.

* At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer.

* During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia.

* During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol.

* During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol.

* Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.

Detailed Description

Not available

Study Timeline

• Status Verified: 2002-10
• Study Start: 2003-02
• Study Completion: 2004-10
• Study First Submitted: 2006-03-14
• Study First Submitted QC: 2006-03-14
• Study First Posted: 2006-03-15
• Last Update Submitted: 2007-03-23
• Last Update Posted: 2007-03-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• All patients admitted to the internal medicine ward with hyperglycemia

Exclusion Criteria

• Patients admitted due to hypoglycemia, hyperosmolar state, and ketoacidosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Mean blood glucose during hospitalization

Secondary Outcome Measures

Name	Time	Method
Hypoglycemic events
Length of in-hospital stay
Infections
Complications (myocardial infarction, stroke)
Disposition at discharge (home, nursing home)

Trial Locations

Locations (1)

Hadassah Medical Organization; 🇮🇱 Jerusalem, Israel