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Targeted Group-based Psychotherapy to Address Emotional Stress in at Risk ICU Survivors

Not Applicable
Withdrawn
Conditions
Post Intensive Care Syndrome
Anxiety
Traumatic Stress
Depression
Interventions
Behavioral: Managing Stress & Emotions Group (MSEG)
Registration Number
NCT05856240
Lead Sponsor
Beth Israel Deaconess Medical Center
Brief Summary

This study is a pilot clinical trial to assess the feasibility of implementing a group-psychotherapy intervention to modify emotional stress (e.g., anxiety, depression, post-traumatic stress) following ICU hospitalization

Detailed Description

Psychological symptoms and emotional distress, including anxiety, depression, and posttraumatic stress, are common problems among patients discharged from the intensive care unit (ICU). The presence of psychological distress is associated with poor medical adherence, slower recovery, and reduced quality of life in this patient population. There is a lack of research on evidence-based interventions to address mental health symptoms in ICU patients post-hospitalization. Researchers have recently highlighted the potential utility of peer support/group interventions in the post-ICU recovery process; however, they have yet to be widely tested in interventional trials, and their feasibility and acceptability in the post-ICU population have yet to be demonstrated in a research study. Thus, the purpose of this study is to adapt and deliver a 6-session group-based psychological intervention for post-ICU patients in a single-arm, non-randomized interventional study. Patients' symptoms will be assessed at baseline, post-intervention, and 3-month follow-up. The primary aim of the study is to assess the feasibility and acceptability of the group intervention in the post-ICU patient population. Secondarily, changes in patients' emotional distress will be examined to assess for the impact of the intervention on patients' symptoms.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Aged at least 18 years
  • ICU stay of at least 3 days
  • Access to a smartphone, laptop, or computer and able to participate in a meeting via a virtual platform
  • Montreal Cognitive Assessment (MoCA)-BLIND score of at least 18
  • English fluency
  • Screening questionnaires consistent with clinically significant depression OR anxiety (Hospital Anxiety and Depression Scale-Depression [HADS-D] OR HADS-Anxiety [HADS- A] score of >7) OR Post-traumatic Stress (PTSD Checklist-Civilian Version [PCL-C] score of ≥ 30)
  • Resides in the state of Massachusetts.
Exclusion Criteria
  • Unable or unwilling to participate in 6 weekly sessions of group therapy
  • Permanent or severe cognitive impairment severe enough to impede participation (as assessed via the MMSE).

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Group-Based Psychological InterventionManaging Stress & Emotions Group (MSEG)Single-arm feasibility trial, so all participants will receive the intervention.
Primary Outcome Measures
NameTimeMethod
Feasibility of recruitmentBaseline

This will be determined by reporting the number of patients who meet study criteria who agreed to participate.

Adherence to sessions (acceptability)At 6 weeks (immediately at end of intervention sessions)

This will be determined by reporting the number of intervention sessions completed by each participant.

Feasibility of data collection at follow-upAt 3 months follow-up

This will be determined by reporting the number of participants who provide follow-up data.

Feasibility of data collection at post-treatmentAt 6 weeks (immediately at end of intervention sessions)

This will be determined by reporting the number of participants who provide post-treatment data.

Client Satisfaction QuestionnaireAt 6 weeks (immediately at end of intervention sessions)

This measure assesses participants' satisfaction with the intervention (participant ratings of 1 to 4, higher scores indicate higher satisfaction).

Credibility and Expectancy QuestionnaireBaseline

This measure assesses participants' expectations and beliefs that the intervention will be helpful (Participant ratings of 1 to 9, higher scores indicate higher beliefs that the intervention will be helpful).

Secondary Outcome Measures
NameTimeMethod
PTSD Checklist-Civilian Version (PCL-C)Change from Baseline to immediately Post-Intervention (at 6 weeks), and from Baseline to to 3-months Follow-up

This measure assesses participants' PTSD symptoms (Participant ratings of 1 to 5, higher ratings indicate greater PTSD symptoms).

Patient-Reported Outcomes Measurement Information System-29 (PROMIS-29)- AnxietyChange from Baseline to immediately Post-Intervention (at 6 weeks), and from Baseline to to 3-months Follow-up

This sub-scale of the PROMIS measure assesses participants' anxiety symptoms (Participant ratings of 1 to 5, higher ratings indicate greater anxiety symptoms).

Patient-Reported Outcomes Measurement Information System-29 (PROMIS-29)- DepressionChange from Baseline to immediately Post-Intervention (at 6 weeks), and from Baseline to to 3-months Follow-up

This sub-scale of the PROMIS measure assesses participants' depression symptoms (Participant ratings of 1 to 5, higher ratings indicate greater depression symptoms).

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