NCT03624166已完成4 期
Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery :Prospective , Randomized Double- Blinded Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- incidence of hypotension
研究概览
简要总结
The purpose of this study is to evaluate the effect of sub anesthetic dose of ketamine on vasopressor (Ephedrine) requirement to prevent maternal hypotension after spinal anesthesia in caesarean section.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Physical status American Society of Anesthesiologist(ASA) I or II. Full term pregnancy
排除标准
- •,Pre-eclampsia.
- •Chronic hypertension.
- •Cardiovascular troubles.
- •any contraindications to spinal anesthesia as back infection , coaguolopathy , patient refusal
研究组 & 干预措施
Ketamine
Active Comparator
sub- anesthetic dose of ketamine 0.5 mg/kg will be given in 3 ml volume
干预措施: Ketamine (Drug)
isotonic saline
Placebo Comparator
isotonic saline 3 ml volume will be given
干预措施: isotonic saline (Drug)
结局指标
主要结局
incidence of hypotension
时间窗: 5 hours
after spinal anesthesia sub- anesthetic dose of ketamine will be given and blood pressure will be recorded every 2 minutes till delivery , every 5 minutes till end of surgery
次要结局
未报告次要终点
研究者
Amin Mohammed Alansary Amin Ahmed Helwa
Assistant Professor
Ain Shams University
研究点 (1)
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