Effects of escitalopram and Citalopram on Depression in Patients with Chronic Kidney Failure under Hemodialysis
Phase 3
- Conditions
- Major depressive disorder, chronic renal failure.Persistent mood [affective] disorders
- Registration Number
- IRCT20200304046698N1
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients with major depressive disorder with minimum depression score of 13 with Hamilton Test and psychiatrist approval
Patients with renal failure who have been undergoing hemodialysis treatment for at least 3 months
Exclusion Criteria
Systemic medical disease (heart disease, diabetes, epilepsy, hypertension, thyroid) that interferes with medication use or follow-up.
Liver failure, Hepatitis B and C, HIV / AIDS
Existence of psychiatric disorder other than depression
Patient being treated with SSRIs (if previously treated after 3 months treatment)
Pregnancy or lactation
Addiction to all kinds of drugs and psychotropics
The occurrence of any unbearable side effects in the patient
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression score on the Hamilton scale. Timepoint: Assessment of Hamilton depression score at baseline and 6 weeks after intervention. Method of measurement: Hamilton Depression Inventory.
- Secondary Outcome Measures
Name Time Method Drug side effect. Timepoint: At baseline (before intervention) and 6 weeks after drug administration. Method of measurement: Questionnaire designed by the researcher.