Treatment Decision-making in Patients With Recurrent High-grade Glioma

Completed

• Conditions: Malignant Glioma; Life Experiences

• Registration Number: NCT04013828
• Lead Sponsor: Odense University Hospital

Brief Summary

This qualitative study explores the lived experience of high-grade glioma patients and their close relatives at time of recurrence. With focus on the decision-making about treatment and care..

Detailed Description

High-Grade Glioma is a life-threatening disease that can cause the patient substantial physical, mentally and psychosocially impairment. The life expectancy is short, and a majority of patients experience recurrence of tumour growth. At time of recurrence, the treatment possibilities can include surgery, oncological treatment and/or palliative care.

In this situation the patients and their close relatives need to make a difficult balancing between benefits and trade offs.

Little is known about how the patients and their close relatives experience the recurrence and the decision-making process.

The objective of this study is therefore to explore the perspectives, experiences and needs in patients and their close relatives in relation to the decision-making process at time of recurrence.

Data will be generated through semi-structured interviews. Interviews will be analysed and interpreted using a Ricoeur inspired method of qualitative analysis.

The study is part of a larger PhD-study.

Study Timeline

• Study Start: 2019-05-06
• Study First Submitted: 2019-07-08
• Study First Submitted QC: 2019-07-08
• Study First Posted: 2019-07-10
• Primary Completion: 2020-04-03
• Status Verified: 2022-04
• Study Completion: 2022-04-08
• Last Update Submitted: 2022-04-19
• Last Update Posted: 2022-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

• The patient is offered surgical treatment (after an assesment done by the multidisciplinary team)
• Able to speak and understand danish
• Able to participate in an interview
• Able to give informed concent for participation

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Exclusion Criteria

• Patients with severe cognitive impairment which prohibits them from either giving informed concent or participating in interview.
• Relatives are excluded if the patient do not give concent for the participation of relatives

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Involvement preferences	Interviews are performed 2-6 weeks after the decision-making	The preferences of patients and relatives for being involved in the decision-making.
Experiences of patients and relatives	Interviews are performed 2-6 weeks after the decision-making	How patients and their close relatives experience the decision-making process

Trial Locations

Locations (2)

Copenhagen University Hospital; Rigshospitalet; 🇩🇰 Copenhagen, Denmark

Odense University Hospital; 🇩🇰 Odense, Denmark